Note: Information on HIV testing may not be consistent with latest technologies.Įvaluation Guide for HIV Testing and Linkage Programs in Nonclinical Settings Supports planning, implementation, and evaluation of HIV testing and linkage services in non-clinical settings. Planning and Implementing HIV Testing and Linkage Programs in Nonclinical Settings: A Guide for Program Managers The purpose of the guide is to familiarize providers with key programmatic issues and updates that impact HIV testing service delivery in nonclinical settings.Ī CDC webpage that provides information and resources for providers and public on HIV testing in nonclinical settings. Grantee guidance to support the implementation of HIV testing services in nonclinical settings in the United States. Implementing HIV Testing in Nonclinical Settings: A Guide for HIV Testing Providers Implementation Resources Title and Description
#WESTERN BLOT TEST FOR HIV UPDATE#
Technical Update on HIV-1/2 Differentiation Assays, August 2016.This technical update provides information on the use of the Alere Determine HIV 1/2 Ag/Ab Combo single use rapid test (Determine) in laboratories where it is not feasible to conduct an instrumented antigen/antibody test as the initial test in the algorithm. Technical Update Laboratory Algorithm for HIV Diagnosis, October 2017.*New Update* Technical Update for HIV Nucleic Acid Tests Approved for Diagnostic Purposes, May 2023.Provides updated recommendations for HIV testing by laboratories in the United States and describes approaches for reporting test results to persons ordering HIV tests and to public health authorities. Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations Provides recommendations on routine, opt-out HIV screening of adults, adolescents, and pregnant women in health care settings in the United States. Revised Recommendations for HIV Testing of Adults, Adolescents, and Pregnant Women in Health Care Settings This MMWR policy note provides an update on CDC’s initiative to assess the benefits and harms associated with more frequent screening of MSM. To learn about current recommendations, please call one of our clinical consultation lines.Recommendations for HIV Screening of Gay, Bisexual, and Other Men Who Have Sex with Men - United States, 2017
This Case of the Month includes consultation based on the most up-to-date evidence at the time of its publication. They do not constitute medical advice and are not to serve as a substitute for medical judgment. HIV infection is unlikely in this scenario and this is likely a false positive 4th generation HIV test.īecause CCC consultations are based on information provided by the caller or clinician accessing the online consultation center, without the benefit of a direct evaluation or examination of the patient, consultations are intended to be used as a guide. False reactivity on the EIA or Western Blot assays can be due to HLA antibody, autoimmune diseases (such as lupus), cross reactivity to yeast, or to other contaminating antigens used to prepare the HIV antigens. Infection is unlikely if any of the bands that usually reveal HIV (p24, gp41, and gp120/160) are negative. If there is significant concern regarding HIV-2 infection, it may be helpful to identify the Western Blot bands, as some patterns can be more suspicious for HIV-2. Also, if using 4th generation testing, the Multispot test is the next stage in the algorithm. type 2 antibodies, as the Multispot is the only test that provides this specificity.
A Multispot follow-up test could be used to differentiate HIV type 1 vs. This is likely a false positive 4th generation test. Given this patient’s risk history, how should these test results be interpreted? CCC consultant advice The patient’s partner had also been sober for 2 years and had negative HIV screening tests multiple times as well. The patient’s viral load was checked and was negative (VL<20).
Once again the test was positive, repetitively reactive ELISA results, and an inconclusive Western Blot test. A repeat 4th generation test was done at the physician’s clinic approximately 6 weeks later. The patient then went to Planned Parenthood with a buccal swab, with negative results. The physician did not have information about which WB bands were reactive. The patient had initially had a 4th generation HIV test that was repeatedly reactive but the Western Blot (WB) was indeterminate.
He had been sober for 2 years at the time of the screening test. You are here: Home › Cases of Interest › Case of the Month: Possible False Positive HIV Test Case of the Month: Possible False Positive HIV TestĪ physician called about HIV screening for a 38-year-old man who wanted to be tested because he was getting married and had a history of injection drug use.
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